Study of the histological effect of liver of white mice experimentally infected with A. fumigatus and treated with Amphotericin B and Trametes sp.
DOI:
https://doi.org/10.54153/sjpas.2021.v3i2.235Keywords:
Aspergillus fumigatus, Amphotericin B, Liver, فطرAspgerillus fumiagtus, white mouseAbstract
This study done to investigate the pathohistological lesions in the liver of white mice infected with Aspergillus fumigatus by two main procedures: intraperitoneal injection, nasal implantation and an oral attempt to treat them with the antifungal AmB and the Trametes sp.The result show that A.fumigatus led to the occurrence of tissue changes represented by the occurrence of degeneration necrosis of hepatocytes hemorrhage large infiltration of inflammatory cells and separation of lining endothelial cells of central vein, WhiصًًًًصصصWwqqaooinckkkkle liver of groups of mice that infected with A.fumigatus and treated with the antifungal AmB and the Trametes sp it showed improvement as degeneration and necrosis of number of hepatocytes. Pycknotic nuclei, enlargement number of Kupffer cells, expansion of some blood sinuses, another histological sections showed the semi normal liver tissue.
Downloads
Published
Issue
Section
License
Copyright (c) 2021 Samarra Journal of Pure and Applied Science
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright Notice
Authors retain copyright and grant the SJPAS journal right of first publication, with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in Samarra Journal of Pure and Applied Science.
The Samarra Journal of Pure and Applied Science permits and encourages authors to archive Pre-print and Post-print items submitted to the journal on personal websites or institutional repositories per the author's choice while providing bibliographic details that credit their submission, and publication in this journal. This includes the archiving of a submitted version, an accepted version, or a published version without any Risks.
