تحضير وتشخيص طيفي وفعالية حيوية لليكاند قاعدة شف المشتق من 5-أمينو-2-فينيل-4,2-ثنائي هيدرو-3هيدروجين -بيرازول-3-ون ومعقداته الفلزية
DOI:
https://doi.org/10.54153/sjpas.2025.v7i1.848الكلمات المفتاحية:
قاعدة شف، معقدات فلزية، فعالية حيوية، تشخيص طيفي و بايرازولالملخص
حضرت ثمانية معقدات جديدة ذات الصيغة العامة[M(L)2(H2O)2] الناتجة من تفاعل ليكاند قاعدة شف الجديد ](اي)-5-((2-هيدروكسي بنزايلدين) امينو)-2- فنيل-2,4- ثنائي هايدرو-3هيدروجين-بايرازول-3-ون[ (L) مع الايونات الفلزية ]المنغنيز, الكادميوم, الخارصين, النحاس, النيكل, الكوبلت, الزئبق الثنائية التكافؤ والبلاتين الرباعي التكافؤ[. تم اشتقاق هذا الليكاند من تفاعل الامين )5-أمينو-2-فينيل-4,2-ثنائي هيدرو-3هيدروجين -بيرازول-3-ون( مع السلسلديهايد والذي يرتبط مع الايونات الفلزية عن طريق ذرتي النتروجين مجموعة الايزوميثين واوكسجين مجموعة الهيدروكسيد لحلقة البايرازولين. تم تشخيص المركبات باستخدام مطيافية طيف الاشعة (IR)وطيف (N.M.R)وطيف الاشعة فوق البنفسجية ومن نتائج القياسات تم اقتراح الشكل الهندسي الثماني السطوح للمعقدات المحضرة. تم اختبار القدرة التثبيطية للمركبات المحضرة ضد نوعين من البكتيريا المختارة المكورات العنقودية الذهبية والإشريكية القولونية وفطر المبيضة، حيث أظهرت النتائج أن قدرة المعقدات الفلزية على تثبيط اعلى من الليكاند.
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