Investigating the prevalence of some Gram-negative bacteria in patients with lower respiratory tract infections in the city of Mosul and studying their sensitivity to antibiotics

Abstract

The study includes the isolation and diagnosis of the dominant Gram-negative bacteria from sputum samples of patients attending Al-Salam Teaching Hospital, Al-Qayyarah General Hospital, and the Chest and Respiratory Diseases Consultation Clinic in the city of Mosul, and those suffering from lower respiratory tract infections, with ages ranging from (1-86) years, for both sexes. The isolates were diagnosed. Based on the apparent culture characteristics, microscopic characteristics and biochemical tests, the diagnostic results were supported using the FITIC-2 system to confirm the identification of the species. (95) isolates were obtained from a total of (218) sputum samples, with a percentage of (43.58%). The type Klebsiella pneumoniae was the most prevalent, with a percentage of 33% (34.7%), followed by the type of Pseudomonas aeruginosa, with a percentage of 25(26.7%), and the types E-coli, Protous maribilis, and Serratia folaontic were the most common. fonticola and Pseudomonas stuzeri at rates of (22.1%), (10.5%), (4.2%) and (2.1%) for each of them, respectively. The resistance and sensitivity of the isolates under study to antibiotics were tested using (9 antibiotics). The results show that Gram-negative bacteria possessed high resistance to the third-generation cephalosporin antibiotics (Ceftraxone and Cefotoxime, at a rate of 88% and 83.2%, respectively, and to the fluoroquinolone antibiotics (Ciprofloxacin and Levofloxacin) at a rate of 84.2% and 86.3%, respectively, and the anti-aminoclacids represented by Amikacin at a rate of 84.2%. The results showed that the anticarbapenems represented by anti-Meropenem were among the most effective antimicrobial agents against Gram-negative isolates.