Evaluation of fructosamine and glycated albumin in prediabetes in Kirkuk city

Abstract

Prediabetes is a condition that causes blood sugar levels to be high but below the threshold defined for diabetes mellitus. Leaving the condition without lifestyle changes puts adults and children with prediabetes at greater risk of developing type 2 diabetes mellitus (T2DM). The study aimed to determine serum levels of fructosamine, glycated albumin, cholesterol, triglycerides, lipoproteins, urea, creatinine and albumin concentrations in prediabetics in Kirkuk city. In addition to studying the association between the variables studied in prediabetes. A total of 21 healthy subjects with glucose within normal limits (control group) and 68 subjects with prediabetes (study group) were included in this study. Levels of serum lipid markers, urea, creatinine, and albumin were measured as part of the routine procedure. In order to measure the levels of fructoseamine and glycated albumin, ELISA technique was used. The results of the study showed that serum levels of fructosamine and glycated albumin were significantly higher in the prediabetes group compared to the control group (p < 0.01). The values of fructosamine and glycated albumin showed a strong positive correlation when compared with their aversion to each other (r = 0.303).